Microscale Biosensor Identifies Listeria.

Food Ingredient News, June, 2004

A microscale biosensor, in development at Purdue University Dept. of Agricultural and Biological Engineering, POTR 1295, 1146 ABE Bldg., West Lafayette, IN 47907-1146; Tel: 765/494-7022, Fax: 765/496-1115), can detect targeted pathogens. It exhibits a particular affinity for Listeria monocytogenes, identifying the bacterium in a few hours, if not within minutes.

The chip-type biosensor consists of a microfluidic system with integrated electronics, inlet-outlet ports, and interface schemes. The microfluidic system provides high sensitivity detection at its semiconductor interfaces.

According to Michael Ladisch, detection sensitivity with the biosensor is enhanced by the following factors: small fluid volumes (on the order of 30 nl); use of a low-conductivity...

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