Setraline treatment o children and adolescents with obsessive-compulsive disorder or depression: pharmacokinetics, tolerability, and efficacy.

Journal of the American Academy of Child and Adolescent Psychiatry,  April, 1998  by Johnston, Hugh F.

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In the United States, mental illness occurs in at least 12% of children and adolescents (7 to 12 million) (Greenberg et al., 1993). Depression and obsessive-compulsive disorder (OCD) are among the most common conditions in young individuals. Depression occurs in approximately 5% and OCD affects 2% to 4% of juveniles (Douglass et al., 1995; Tadai et al., 1995; Wilson et al., 1995).

The clinical characteristics of depression and OCD are similar in pediatric and adult patients (March et al., 1995; Moreau, 1990), and if untreated in children, they can have an impact on both educational ...

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