Brain magnetic resonance spectroscopy in Tourette's disorder.

Journal of the American Academy of Child and Adolescent Psychiatry,  December, 2005  by DeVito, Timothy J.; Drost, Dick J.; Pavlosky, William; Neufeld, Richard W.J.; Rajakumar, Nagalingam; McKinlay, B. Duncan; Williamson, Peter C.; Nicolson, Rob

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Tourette's disorder, with a prevalence of 1%-3% of children and adolescents (Robertson, 2003), is a chronic, childhood-onset neuropsychiatric illness

that is characterized by motor and vocal tics with fluctuating severity. It is frequently comorbid with obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) and is more prevalent in males.

Although the neurobiological abnormalities underlying Tourette's disorder remain unknown, various neuroimaging, neurophysiological, and biochemical studies have suggested an important role for the basal ...

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