Promising strategies to minimize secondary brain injury after head trauma.

Bayir, H., Clark, R., Kochanek, P. Critical Care Medicine, 2003, 31 (1), S112-S117.

REVIEWER INTRODUCTION: Traumatic brain injury (TBI) is a pervasive health problem. The devastating effects of TBI often remain evident throughout the remainder of a patient's life. TBI occurs in two phases, the primary injury or assault followed by a cascade of pathophysiological changes leading to secondary brain injury. To date therapies have not met the challenges that occur in TBI. Authors of this article reviewed eighty-three studies to seek innovative therapeutic methods for the treatment ...