Designer drugs: a silver lining. (development of phencyclidine) (Science and Technology)

Economist (US), The, January, 1989

Designer drugs A silver lining

ON THE streets of San Francisco it is called "killer", having formerly been known as "angel dust". The less attractive name comes from some particularly unpleasant effects which befall those who use a lot of it too often. In the laboratory of Dr Edward Domino at the University of Michigan it is called phencyclidine (PCP). Some of his recent research, which he described at the AAAS conference, suggests that a better name might be "saver" - at least for some.

The drugs was first developed as an anaesthetic by an American pharmaceutical firm, Parke-Davis, in the 1950s. Despite some promising trials on animals, it turned out to make people delirious when they woke up. Just when Parke-Davis stopped producing it, the basement...

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