San Diego public stocks

San Diego Business Journal, Sept 22, 2008

Index Watch

Index                              8/16/08    9/09/08

San Diego Business Journal Index   1636.45    1605.46
Dow Jones Industrial Average       11059.02   11230.73
S&P 500 Index                      1213.60    1224.51
NASDAQ Composite                   2207.90    2209.81

Index                              Net Charge   % Change

San Diego Business Journal Index     30.99        1.93%
Dow Jones Industrial Average        -171.71      -1.53%
S&P 500 Index                        -10.91      -0.89%
NASDAQ Composite                     -1.91       -0.09%

Market Trends

  Date       SDBJ     S&P 500   NASDAQ      DJI

9/16/2008   1636.45   1213.60   2207.90   11059.02
9/9/2008    1605.46   1224.51   2209.81   11230.73
9/2/2008    1727.15   1277.57   2349.24   11516.92
8/26/2008   1766.30   1271.51   2361.97   11412.87
8/19/2008   1790.46   1266.69   2384.36   11348.55
8/12/2008   1796.34   1289.59   2430.61   11642.47
8/5/2008    1804.77   1284.88   2349.83   11615.77
7/29/2008   1775.40   1263.19   2319.62   11397.56

Top Gainers & Losers

Top Dollar Gainers
Amylin Pharmaceuticals Inc.        2.35
Qualcomm Inc.                      2.31
Sequenom Inc.                      2.29
NuVasive Inc.                      2.16
WD-40 Co.                          2.14

Top Percentage Gainers
Acadia Pharmaceuticals Inc.       17.00%
ImageWare Systems Inc.            13.33%
Amylin Pharmaceuticals Inc.       12.45%
Santarus Inc.                     11.54%
Sequenom Inc.                     11.09%

Top Dollar Losers
PICO Holdings Inc.                -5.06
Sempra Energy                     -4.16
RF Industries Ltd.                -2.40
1st Pacific Bancorp               -2.07
Invitrogen Corp.                  -2.00

Top Percentage Losers
1st Pacific Bancorp              -31.22%
RF Industries Ltd.               -31.09%
Microlslet Inc.                  -29.41%
Vical Inc.                       -25.96%
Medicinova Inc.                  -23.29%

Market Recap
Advancers                         27
Decliners                         59
Unchanged                          3

           TICKER
EXCHANGE   SYMBOL     COMPANY NAME

NASD       FPBN       1ST PACIFIC BANCORP
NASD       ACRD       ACADIA PHARMACEUTICALS INC.
NASD       ACCL       ACCELRYS INC.
AMEX       ANX        ADVENTRX PHARMACEUTICALS INC.
NASD       ALDA       ALDILA INC.
NASD       ATEC       ALPHATECH HOLDINGS INC.
NASD       ATCO       AMERICAN TECHNOLOGY CORP.
NYSE       AHS        AMN HEALTHCARE SERVICES INC.
NASD       AMLN       AMYLIN PHARMACEUTICALS INC.
NASD       ANDS       ANADYS PHARMACEUTICALS INC.
NASD       ARNA       ARENA PHARMACEUTICALS INC.
NASD       ASHW       ASHWORTH INC.
NASD       AVNR       AVANIR PHARMACEUTICALS
AMEX       AFT        AXESSTEL INC.
NYSE       BMR        BIOMED REALTY TRUST INC.
NASD       CADX       CADENCE PHARMACEUTICALS INC.
NYSE       ELY        CALLAWAY GOLF CO.
NASD       CDIC       CARDIODYNAMICS INTERNATIONAL CORP.
AMEX       CXM        CARDIUM THERAPEUTICS INC.
NASD       CHIC       CHARLOTTE RUSSE HOLDING INC.
NASD       COHU       COHU INC.
AMEX       CUB        CUBIC CORP.
NASD       CYMI       CYMER INC.
NASD       CYPB       CYPRESS BIOSCIENCES INC.
OTC        DFCO.PK    DALRADA FINANCIAL CORP.
NASD       DXCM       DEXCOM INC.
NASD       DRAD       DIGIRAD CORP.
NASD       DEIX       DEI HOLDINGS INC.
NASD       DIVX       DIVX INC.
NASD       HILL       DOT HILL SYSTEMS CORP.
NASD       ECPG       ENCORE CAPITAL GROUP INC.
NASD       FPTB       FIRST PACTRUST BANCORP INC.
NASD       GXDX       GENOPTIX INC.
NASD       GPRO       GEN-PROBE INC.
NASD       HALO       HALOZYME THERAPEUTICS
NASD       HEPH       HOLLIS-EDEN PHARMACEUTICALS INC.
NASD       IDMI       IDM PHARMA INC.
NASD       ILMN       ILLUMINA INC.
OTC        IWSYE.OB   IMAGEWARE SYSTEMS INC.
NYSE       IMP        IMPERIAL CAPITAL BANCORP INC.
NASD       IFON       INFOSONICS CORP.
AMEX       INO        INOVIO BIOMEDICAL CORP.
NASD       IVGN       INVITROGEN CORP.
NASD       ISIS       ISIS PHARMACEUTICALS INC.
NYSE       JBX        JACK IN THE BOX INC.
OTC        JAVO.OB    JAVO BEVERAGE CO. INC.
OTC        JMAR.OB    JMAR TECHNOLOGIES INC.
NASD       KTOS       KRATOS DEFENSE & SECURITY SOLUTIONS INC.
NASD       UPC        LA JOLLA PHARMACEUTICAL CO.
NASD       LEAP       LEAP WIRELESS INTERNATIONAL INC.
NASD       MXWL       MAXWELL TECHNOLOGIES INC.
NASD       MNOV       MEDICINOVA INC.
NASD       MBRX       METABASIS THERAPEUTICS INC.
OTC        MIIS.OB    MICROISLET INC.
NASD       MITI       MICROMET INC.
NASD       NGEN       NANOGEN INC.
NASD       NAZI       NATURAL ALTERNATIVES INTERNATIONAL INC.
NASD       NBIX       NEUROCRINE BIOSCIENCES INC.
NASD       NIGH       NITCHES INC.
NASD       NVTL       NOVATEL WIRELESS INC.
AMEX       NTN        NTN BUZZTIME INC.
NASD       NUVA       NUVASIVE INC.
NASD       OPTR       OPTIMER PHARMACEUTICALS INC.
NASD       OREX       OREXIGEN THERAPEUTICS INC.
NASD       OVRL       OVERLAND STORAGE INC.
NASD       PACW       PACWEST BANCORP
OTC        PTSC.OB    PATRIOT SCIENTIFIC CORP.
AMEX       PXG        PHOENIX FOOTWEAR GROUP INC.
NASD       PICO       PICO HOLDINGS INC.
NASD       PSMT       PRICESMART INC.
NASD       PURE       PURE BIOSCIENCE
NASD       OCOM       QUALCOMM INC.
NASD       QDEL       QUIDEL CORP.
NYSE       O          REALTY INCOME CORP.
NYSE       RMD        RESMED INC.
NASD       RAIL       RF INDUSTRIES LTD.
NASD       ROYL       ROYALE ENERGY INC.
NASD       RUBO       RUBIO'S RESTAURANTS INC.
NYSE       SAI        SAIC INC.
NASD       SLATS      SANTARUS INC.
NYSE       SRE        SEMPRA ENERGY
NASD       SNMX       SENOMYX INC.
NASD       SONM       SEQUENOM INC.
OTC        SHSO.PK    SOUND HEALTH SOLUTIONS
OTC        TDLR.OB    TRANSDEL PHARMACEUTICALS INC.
NASD       VSAT       VIASAT INC.
NASD       VICL       VICAL INC.
NASD       WDFC       WD-40 CO.
NASD       WBSN       WEBSENSE INC.

             PRICE      PRICE      NET     PERCENT
EXCHANGE   9/16/2008   9/5/2008   CHANGE   CHANGE

NASD            4.56       6.63    -2.07   -31.22%
NASD            2.96       2.53     0.43    17.00%
NASD            4.76       5.03    -0.27    -5.37%
AMEX            0.25       0.25     0.00     0.00%
NASD            4.18       3.94     0.24     6.09%
NASD            4.31       4.57    -0.26    -5.69%
NASD            0.65       0.67    -0.02    -2.99%
NYSE           19.00      18.79     0.21     1.12%
NASD           21.23      18.88     2.35    12.45%
NASD            2.64       2.38     0.26    10.92%
NASD            5.80       5.75     0.05     0.87%
NASD            3.10       3.99    -0.89   -22.31%
NASD            0.79       0.90    -0.11   -12.22%
AMEX            0.72       0.78    -0.06    -7.69%
NYSE           27.15      27.28    -0.13    -0.48%
NASD            9.95       9.93     0.02     0.20%
NYSE           13.69      14.40    -0.71    -4.93%
NASD            1.50       1.44     0.06     4.17%
AMEX            1.70       1.84    -0.14    -7.61%
NASD           11.99      12.78    -0.79    -0.18%
NASD           14.93      15.77    -0.84    -5.33%
AMEX           27.26      28.59    -1.33    -4.65%
NASD           26.58      26.74    -0.16    -0.60%
NASD            6.23       6.46    -0.23    -3.56%
OTC             0.04       0.05    -0.01   -20.00%
NASD            6.74       6.83    -0.09    -1.32%
NASD            1.42       1.41     0.01     0.71%
NASD            1.07       1.38    -0.31   -22.46%
NASD            7.24       7.63    -0.39    -5.11%
NASD            1.94       2.18    -0.24   -11.01%
NASD           12.58      13.62    -1.04    -7.64%
NASD           11.90      12.63    -0.73    -5.78%
NASD           32.54      33.54    -1.00    -2.98%
NASD           56.31      56.15     0.16     0.28%
NASD            7.48       7.39     0.09     1.22%
NASD            1.30       1.48    -0.18   -12.16%
NASD            2.50       2.32     0.18     7.76%
NASD           83.41      82.21     1.20     1.46%
OTC             0.51       0.45     0.06    13.33%
NYSE            8.67       9.13    -0.46    -5.04%
NASD            0.52       0.59    -0.07   -11.86%
AMEX            0.80       0.89    -0.09   -10.11%
NASD           38.84      40.84    -2.00    -4.90%
NASD           16.45      17.12    -0.67    -3.91%
NYSE           24.84      25.40    -0.56    -2.20%
OTC             0.48       0.50    -0.02    -4.00%
OTC             0.12       0.15    -0.03   -20.00%
NASD            1.85       2.11    -0.26   -12.32%
NASD            1.35       1.63    -0.28   -17.18%
NASD           44.48      46.01    -1.53    -3.33%
NASD           11.11      10.60     0.51     4.81%
NASD            2.80       3.65    -0.85   -23.29%
NASD            1.40       1.50    -0.10    -0.67%
OTC             0.12       0.17    -0.05   -29.41%
NASD            4.99       5.24    -0.25    -4.77%
NASD            0.29       0.30    -0.01    -3.33%
NASD            7.37       7.50    -0.13    -1.73%
NASD            5.43       5.60    -0.17    -3.04%
NASD            1.14       1.14     0.00     0.00%
NASD            5.89       6.10    -0.21    -3.44%
AMEX            0.22       0.21     0.01     4.76%
NASD           50.75      48.59     2.16     4.45%
NASD            8.35       8.07     0.28     3.47%
NASD           10.01       9.45     0.57     5.98%
NASD            0.73       0.85    -0.12   -14.12%
NASD           30.00      30.59    -0.59    -1.93%
OTC             0.20       0.24    -0.04   -16.67%
AMEX            1.10       1.12    -0.02    -1.79%
NASD           39.91      44.97    -5.06   -11.25%
NASD           19.21      20.42    -1.21    -5.93%
NASD            3.65       4.02    -0.37    -9.20%
NASD           47.92      45.61     2.31     5.06%
NASD           16.61      16.79    -0.18    -1.07%
NYSE           26.29      25.30     0.99     3.91%
NYSE           47.40      45.52     1.88     4.13%
NASD            5.32       7.72    -2.40   -31.09%
NASD            4.10       4.63    -0.53   -11.45%
NASD            5.98       6.12    -0.14    -2.29%
NYSE           20.31      20.22     0.09     0.45%
NASD            2.90       2.60     0.30    11.54%
NYSE           53.04      57.20    -4.16    -7.27%
NASD            4.10       4.09     0.01     0.24%
NASD           22.93      20.64     2.29    11.09%
OTC             0.01       0.01     0.00     0.00%
OTC             1.35       1.45    -0.10    -6.90%
NASD           25.47      25.56    -0.09    -0.35%
NASD            2.31       3.12    -0.81   -25.96%
NASD           37.81      35.67     2.14     6.00%
NASD           21.89      22.06    -0.17    -0.77%

           52-WEEK   52-WEEK
EXCHANGE     HIGH      LOW

NASD         15.50      5.51
NASD         16.56      2.30
NASD          8.24      4.24
AMEX          2.70      0.23
NASD         18.36      3.65
NASD          6.53      3.35
NASD          4.19      0.56
NYSE         20.05     14.25
NASD         51.10     18.55
NASD          3.13      1.36
NASD         12.22      4.55
NASD          6.49      2.47
NASD          2.84      0.75
AMEX          1.15      0.19
NYSE         28.25     19.32
NASD         15.70      4.84
NYSE         18.20     10.63
NASD          4.55      0.70
AMEX          3.19      1.45
NASD         20.61      9.90
NASD         20.75     13.27
AMEX         50.68     20.58
NASD         44.73     22.86
NASD         15.60      6.17
OTC           0.70      0.03
NASD         10.91      3.69
NASD          4.68      1.36
NASD          4.90      0.99
NASD         19.35      6.12
NASD          4.12      1.95
NASD         14.19      6.10
NASD         26.35     10.44
NASD         39.79     20.41
NASD         71.84     44.82
NASD          9.70      4.19
NASD          2.87      1.30
NASD          3.88      0.57
NASD         95.75     50.34
OTC           2.00      0.25
NYSE         36.14      2.75
NASD          3.80      0.52
AMEX          1.70      0.50
NASD         49.58     36.73
NASD         20.15     10.91
NYSE         35.13     17.79
OTC           1.23      0.42
OTC           0.28      0.04
NASD          3.09      1.33
NASD          4.60      1.45
NASD         85.48     29.87
NASD         14.75      7.10
NASD          9.00      2.75
NASD          3.33      0.83
OTC           0.74      0.11
NASD          7.74      1.22
NASD          1.99      0.24
NASD          9.20      5.85
NASD         13.07      4.00
NASD          3.38      0.50
NASD         27.20      5.80
AMEX          0.98      0.20
NASD         57.82     31.17
NASD          9.70      5.85
NASD         18.45      6.89
NASD          2.88      0.71
NASD         62.56     11.30
OTC           0.94      0.15
AMEX          3.35      0.99
NASD         48.24     28.62
NASD         33.67     17.12
NASD          8.72      2.58
NASD         56.88     35.17
NASD         21.22     13.50
NYSE         30.70     20.27
NYSE         54.58     20.51
NASD          8.98      5.03
NASD         14.70      2.18
NASD         10.99      4.25
NYSE         21.90     17.33
NASD          3.24      1.78
NYSE         64.21     48.58
NASD         12.68      3.66
NASD         24.61      4.86
OTC           0.13      0.01
OTC           3.50      1.05
NASD         36.49     19.06
NASD          5.23      2.39
NASD         42.70     26.50
NASD         22.93     15.43

             SHARES      MARKET ($000)
EXCHANGE   OUTSTANDING   CAPITALIZATION

NASD         4970          22663.2
NASD         37130         109904.8
NASD         27080         128900.8
AMEX         90250         22562.5
NASD         5160          21568.8
NASD         47420         204380.2
NASD         30540         19851
NYSE         33740         641060
NASD         137240        2913605.2
NASD         28770         75952.8
NASD         73950         428910
NASD         14750         45725
NASD         78200         61778
AMEX         23230         16725.6
NYSE         71720         1947198
NASD         38360         381682
NYSE         64800         887112
NASD         7240          10860
AMEX         46930         79781
NASD         20870         250231.3
NASD         23210         346525.3
AMEX         26730         728659.8
NASD         29630         787565.4
NASD         37880         235992.4
OTC          5140          205.6
NASD         29680         200043.2
NASD         18930         26880.6
NASD         25510         27295.7
NASD         32190         233055.6
NASD         46060         89356.4
NASD         23020         289591.6
NASD         4300          51170
NASD         16530         537886.2
NASD         54210         3052565.1
NASD         80390         601317.2
NASD         29080         37804
NASD         25180         62950
NASD         57160         4767715.6
OTC          18080         9220.8
NYSE         5430          47078.1
NASD         14910         7753.2
AMEX         43890         35112
NASD         92310         3585320.4
NASD         95650         1573442.5
NYSE         56710         1408676.4
OTC          159600        76608
OTC          57130         6855.6
NASD         104960        194176
NASD         55330         74695.5
NASD         69210         3078460.8
NASD         21140         234865.4
NASD         11960         33488
NASD         35040         49056
OTC          55020         6602.4
NASD         40870         203941.3
NASD         77060         22347.4
NASD         7020          51737.4
NASD         38440         208729.2
NASD         6020          6862.8
NASD         32540         191660.6
AMEX         55650         12243
NASD         35880         1820910
NASD         29700         247995
NASD         34320         343543.2
NASD         12760         9314.8
NASD         27200         816000
OTC          387450        77490
AMEX         8380          9218
NASD         18840         751904.4
NASD         29690         570344.9
NASD         29300         106945
NASD         1640000       78588800
NASD         32490         539658.9
NYSE         101340        2664228.6
NYSE         75560         3581544
NASD         3290          17502.8
NASD         8500          34850
NASD         9950          59501
NYSE         404370        8212754.7
NASD         51530         149437
NYSE         246380        13067995.2
NASD         30590         125419
NASD         56800         1302424
OTC          3480          34.8
OTC          15550         20992.5
NASD         30720         782438.4
NASD         40350         93208.5
NASD         16440         621596.4
NASD         45050         986144.5

Source: Trade Trends Inc. 509-327-1279