Diagnosis by a nose; Clinic doc develops breath test to detect lung cancer.(News)(Brief Article)

Crain's Cleveland Business, June, 2005

An "electronic nose'' developed in Cleveland can identify people with lung cancer by detecting distinct characteristics in their exhaled breath, according to a story posted last week on Forbes.com. "Based on prior work, we hypothesized that an `electronic nose' would detect lung cancer on the basis of complex `smellprints' of numerous volatile organic compounds in exhaled breath from individuals with lung cancer, as compared with individuals with other, noncancer lung disease or healthy controls,'' said the product's developer, Dr.

Serpil C. Erzurum of the Cleveland Clinic Foundation. Dr. Erzurum and colleagues "tested the device on 14 people with lung cancer and 62 people without cancer. Of the 14 cancer patients, 10 had a positive exhaled breath test and...

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