Manufacturing Industry

US pharma major Pfizer has been granted a worldwide licence for a cancer vaccine candidate CDX-110, which is currently in Phase II development for the treatment of glioblastoma multiforme, by Celldex Therapeutics, which in Q1 2008 became a subsidiary of US vaccine developer Avant Immunotherapeutics

Chemistry and Industry, June 9, 2008

US pharma major Pfizer has been granted a worldwide licence for a cancer vaccine candidate CDX-110, which is currently in Phase II development for the treatment of glioblastoma multiforme, by Celldex Therapeutics, which in Q1 2008 became a subsidiary of US vaccine developer Avant Immunotherapeutics.

CDX-110, which targets the tumour-specific molecule EGFRvlII, has been granted Fast Track and Orphan Drug status by the US Food & Drug Administration. The licence gives Pfizer the right to use EGFRvlII vaccines in other potential indications.

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