Cationic steroid antimicrobial coatings protect medical devices.(Ceragenix Pharmaceuticals develops Ceragenin cationic steroid antimicrobials )(Brief article)
Ceragenin, a new class of compounds known as cationic steroid antimicrobials (CSAs), has been designed for implantable medical devices by Ceragenix Pharmaceuticals, Denver, Colo. The company cited a 21-day study showing that an untreated control catheter had 30,000 bacterial colony forming units (CFUs) on its surface, while treated catheters had fewer than 100 CFUs. These results demonstrate the potential for Ceragenins to be utilized as an antimicrobial treatment for indwelling medical devices. The company ...