Gene Thought to Assist Chemo May Help Cancer Thrive

U.S. Newswire, May, 2007

To: HEALTH/MEDICAL EDITORS

Contact: David Terraso of Georgia Institute of Technology, 1-404- 385-2966, David.Terraso@icpa.gatech.edu

ATLANTA, May 18 /PRNewswire-USNewswire/ -- A gene thought to be essential in helping chemotherapy kill cancer cells may actually help them thrive. In a new study of chemo patients, scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute found that 70 percent of subjects whose tumors had mutations in the gene p53 were still alive after five years. Patients with normal p53 displayed only a 30 percent survival rate. The findings raise the possibility of a new strategy for fighting cancer -- namely, developing drugs to disable the functioning of this gene in the tumors of patients undergoing chemotherapy. The...

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