Team Uncovers Important Secret in Gene Replication
U.S. Newswire, June, 2007
To: EDUCATION EDITORS
Contact: Mary Jane Gore of the University of Virginia Health System, 1-434-924-9241, mjgore@virginia.edu
CHARLOTTESVILLE, Va., June 15 /PRNewswire-USNewswire/ -- A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time. It turns out that it is not just the sequence of the bases (building blocks) in the DNA, but also how loosely or tightly the chromatin (the material that makes up chromosomes) is packed at different points of the chromosome that is critical.
Where chromatin is packed more loosely, the genes are replicated earlier than other genes and are expressed at high levels. Where chromatin is dense, these genes are...
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