One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

U.S. Newswire, May, 2009

To: MEDICAL EDITORS

Contact: Jessica Otitigbe of Rensselaer Polytechnic Institute, 1- 518-276-6050, otitij@rpi.edu

TROY, N.Y., May 8 /PRNewswire-USNewswire/ -- For more than 10 years, Mark Wentland, professor of chemistry and chemical biology at Rensselaer Polytechnic Institute, led a Rensselaer team in the discovery of a family of novel opioid receptor compounds with the potential to treat nervous system disorders and addiction. The family of compounds was licensed to Alkermes Inc., and the company identified a lead product candidate from the library. Clinical trials with the candidate, known as ALKS 33, began in December 2008.

Wentland said the "eureka moment" occurred with the realization that an opioid drug that his group discovered had triggered...

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