UNSW research finds Biosignal's furanones as potential new class of human antibiotics.(University of New South Wales)

BIOTECH Patent News, December, 2004

Biosignal Limited (Sydney, Australia) has been advised that early stage laboratory research led by Dr Diane McDougald, a senior research associate in the Centre for Marine Biofouling and Bio-Innovation at the University of New South Wales, has demonstrated the efficacy of Biosignal's furanones against bacteria that cause cholera.

The key conclusions of the research are:

The lab tests have demonstrated that when the bacteria that cause cholera-Vibrio cholera-are exposed to furanones, they cannot switch on the so-called virulence factors that trigger infection and disease development. The discovery is now being tested in further trials involving mice and tissue cultures. Publication in a scientific journal is pending.

The anti-biofilm activity...

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