Manufacturing Industry
Profit taking makes for mixed IBO stock indexes
Instrument Business Outlook, August 31, 2008
Market 52 Week
Value
Company: Exchange (US $000s) Low High
Laboratory Instrumentation
Affymetrix: o $653,811 7.24 28.12
Applied Biosystems: n $6,392,583 28.75 37.67
Beckman Coulter: n $4,665,785 60.27 77.14
Bio-Rad Laboratories: a $2,447,042 75.65 115.23
Bruker BioSciences: o $2,286,353 6.94 16.66
Caliper Life Sciences: o $189,302 2.15 6.24
Cepheid: o $976,764 15.35 33.36
Combimatrix: n $67,407 4.50 14.48
Dionex: o $1,320,324 62.03 88.39
Harvard Bioscience: o $156,596 3.62 5.20
Illumina: o $6,218,922 46.00 95.75
Luminex o $779,284 14.00 25.63
MOCON: o $58,277 9.63 12.26
0.I. Corp: o $28,822 9.42 13.95
PerkinElmer: n $3,470,553 21.88 30.00
Sequenom: o $1,007,060 4.80 24.50
Starlims: a $68,791 5.73 12.66
Symyx Technologies: o $320,003 5.79 11.42
Thermo Fisher Scientific: n $26,459,344 46.63 62.77
Transgenomic: o $36,894 0.41 0.87
Varian Inc.: o $1,468,563 42.02 78.27
Waters: n $6,765,873 42.02 78.27
X-Rite: n $100,769 1.10 16.22
Process/Metrology/Motion
Instrumentation
FEI Company: o $1,048,102 19.79 34.46
ICx Technologies: n $249,831 3.81 15.50
MTS Systems: o $725,702 29.35 46.29
Nanometrics: o $81,422 3.12 11.71
RAE Systems: n $70,209 1.03 3.68
Strategic Diagnostics: o $59,276 2.30 6.46
Veeco Instruments: o $514,285 12.04 20.50
Zygo: o $184,635 8.80 13.89
Lab Consumables/Equipment
Invitrogen: o $4,307,671 36.73 49.58
Kewaunee Scientific : o $28,759 9.73 20.73
Millipore: n $3,918,003 63.82 83.20
Pall: n $5,018,507 33.37 44.55
QIAGEN: o $3,854,318 16.72 23.83
Sigma-Aldrich: o $7,908,348 43.40 63.04
Techne: o $3,109,868 58.92 82.92
Diversified Instrumentation
Agilent Technologies: n $13,349,600 28.79 39.32
AMETEK: n $5,070,767 37.09 53.12
Danaher: n $26,806,287 67.76 89.22
Mettler-Toledo Int'l: n $3,813,530 86.26 119.84
Roper Industries: n $5,775,270 48.45 71.01
Teledyne Technologies: n $2,295,850 42.89 66.21
Laboratory Instrumentation
Stock Index
Process/Metrology/Motion
Instrumentation
Lab Consumables/Equipment
Stock Index
Diversified Instrumentation
Stock Index
Dow Jones Industrial Average
S&P 500
NASDAQ Composite
Price Change Change
Company: Exchange 6/30/2008 1 Month YTD
Laboratory Instrumentation
Affymetrix: o $8.58 9% -63%
Applied Biosystems: n $36.49 -1% 8%
Beckman Coulter: n $73.82 2% 1%
Bio-Rad Laboratories: a $107.60 21% 4%
Bruker BioSciences: o $15.44 12% 16%
Caliper Life Sciences: o $2.99 -25% -46%
Cepheid: o $18.60 9% -29%
Combimatrix: n $14.36 28% 89%
Dionex: o $65.19 -6% -21%
Harvard Bioscience: o $4.58 -8% 0%
Illumina: o $86.13 -8% 45%
Luminex o $25.49 16% 57%
MOCON: o $10.99 7% -3%
0.I. Corp: o $12.05 11% -7%
PerkinElmer: n $28.41 -2% 9%
Sequenom: o $22.73 6% 138%
Starlims: a $7.49 -4% -29%
Symyx Technologies: o $11.05 16% 44%
Thermo Fisher Scientific: n $60.56 0% 5%
Transgenomic: o $0.74 -1% 37%
Varian Inc.: o $49.71 1% -24%
Waters: n $68.25 0% -14%
X-Rite: n $4.02 16% -65%
Process/Metrology/Motion
Instrumentation
FEI Company: o $27.08 7% 9%
ICx Technologies: n $8.23 11% -14%
MTS Systems: o $41.48 -1% -3%
Nanometrics: o $3.63 -17% -63%
RAE Systems: n $2.01 69% -26%
Strategic Diagnostics: o $2.41 -17% -55%
Veeco Instruments: o $16.81 3% 1%
Zygo: o $10.48 -3% -16%
Lab Consumables/Equipment
Invitrogen: o $42.46 -4% -9%
Kewaunee Scientific : o $14.09 26% -28%
Millipore: n $75.01 7% 3%
Pall: n $40.61 0% 1%
QIAGEN: o $21.16 13% 1%
Sigma-Aldrich: o $56.76 -7% 4%
Techne: o $77.17 -3% 17%
Diversified Instrumentation
Agilent Technologies: n $34.76 4% -5%
AMETEK: n $48.54 1% 4%
Danaher: n $81.57 2% -7%
Mettler-Toledo Int'l: n $105.20 -2% -8%
Roper Industries: n $59.08 -3% -6%
Teledyne Technologies: n $62.33 -1% 17%
Laboratory Instrumentation
Stock Index 643.46 0.7% -2.0%
Process/Metrology/Motion
Instrumentation 379.52 5.3% -4.1%
Lab Consumables/Equipment
Stock Index 511.67 -0.8% 1.3%
Diversified Instrumentation
Stock Index 113.36 -0.3% -5.1%
Dow Jones Industrial Average 11543.55 1.5% -13.0%
S&P 500 1282.83 1.2% -12.6%
NASDAQ Composite 2367.52 1.8% -10.7%
EPS EPS
Company: Exchange P/E 12 Month FY
Laboratory Instrumentation
Affymetrix: o 11 0.77 0.17
Applied Biosystems: n 21 1.78 1.78
Beckman Coulter: n 24 3.04 3.30
Bio-Rad Laboratories: a 27 4.01 3.41
Bruker BioSciences: o 30 0.52 0.59
Caliper Life Sciences: o N/A -0.52 -0.51
Cepheid: o N/A -0.46 -0.50
Combimatrix: n N/A -1.71 -2.10
Dionex: o 24 2.77 2.77
Harvard Bioscience: o N/A -0.05 -0.04
Illumina: o 125 0.69 -5.14
Luminex o 116 0.22 -0.08
MOCON: o 16 0.70 0.67
0.I. Corp: o 71 0.17 0.20
PerkinElmer: n 24 1.18 1.11
Sequenom: o N/A -0.70 -0.54
Starlims: a 14 0.54 0.57
Symyx Technologies: o 29 0.38 0.56
Thermo Fisher Scientific: n 28 2.18 1.76
Transgenomic: o N/A -0.02 -0.04
Varian Inc.: o 24 2.04 2.05
Waters: n 23 2.98 2.62
X-Rite: n N/A -1.51 -0.72
Process/Metrology/Motion
Instrumentation
FEI Company: o 27 1.00 1.36
ICx Technologies: n N/A -1.29 -2.85
MTS Systems: o 16 2.53 2.29
Nanometrics: o N/A -1.01 -0.22
RAE Systems: n N/A -0.15 -0.18
Strategic Diagnostics: o N/A -0.04 0.04
Veeco Instruments: o N/A -0.55 -0.56
Zygo: o 55 0.19 0.79
Lab Consumables/Equipment
Invitrogen: o 13 3.22 2.69
Kewaunee Scientific : o 11 1.34 1.23
Millipore: n 27 2.78 2.48
Pall: n 31 1.32 1.02
QIAGEN: o 96 0.22 0.28
Sigma-Aldrich: o 23 2.52 2.34
Techne: o 29 2.64 2.64
Diversified Instrumentation
Agilent Technologies: n 21 1.69 1.57
AMETEK: n 21 2.34 2.12
Danaher: n 21 3.92 3.72
Mettler-Toledo Int'l: n 20 5.29 4.70
Roper Industries: n 20 2.95 2.68
Teledyne Technologies: n 20 3.14 2.72
Laboratory Instrumentation
Stock Index 27
Process/Metrology/Motion
Instrumentation 22
Lab Consumables/Equipment
Stock Index 23
Diversified Instrumentation
Stock Index 20
Dow Jones Industrial Average
S&P 500
NASDAQ Composite
LTD/ FY R&D/
Company: Exchange Equity ROE Sales
Laboratory Instrumentation
Affymetrix: o 67% 2% 20%
Applied Biosystems: n 18% 20% 9%
Beckman Coulter: n 88% 15% 10%
Bio-Rad Laboratories: a 52% 10% 10%
Bruker BioSciences: o 94% 17% 11
Caliper Life Sciences: o 7% N/A 18%
Cepheid: o 2% N/A 24%
Combimatrix: n 1% N/A 100%
Dionex: o 18% 27% 8%
Harvard Bioscience: o 4% N/A 4%
Illumina: o 3% N/A 20%
Luminex o 4% N/A 21
MOCON: o 1% 15% 7%
0.I. Corp: o 0% 3% 12%
PerkinElmer: n 51% 8% 6%
Sequenom: o 15% N/A 35%
Starlims: a 2% 10% 12%
Symyx Technologies: o 4% 7% 53%
Thermo Fisher Scientific: n 31% 5% 2%
Transgenomic: o 1% N/A 13%
Varian Inc.: o 11% 10% 7%
Waters: n 122% 46% 5%
X-Rite: n 334% N/A 14%
Process/Metrology/Motion
Instrumentation
FEI Company: o 32% 12% 14%
ICx Technologies: n N/A N/A 15
MTS Systems: o 12% 22% 5
Nanometrics: o 1% N/A 13%
RAE Systems: n 20% N/A 9%
Strategic Diagnostics: o 4% 2% 11%
Veeco Instruments: o 45% N/A 15
Zygo: o 2% 9% 12%
Lab Consumables/Equipment
Invitrogen: o 70% 8% 9%
Kewaunee Scientific : o 23% 12% 0%
Millipore: n 108% 12% 7%
Pall: n 103% 12% 3%
QIAGEN: o 82% 4% 10%
Sigma-Aldrich: o 24% 19% 3%
Techne: o N/A 21% 9%
Diversified Instrumentation
Agilent Technologies: n 46% 20% 13%
AMETEK: n 66% 18% 5%
Danaher: n 48% 15% 5
Mettler-Toledo Int'l: n 136% 31% 5%
Roper Industries: n 48% 14% 3%
Teledyne Technologies: n 87% 19% 4%
Laboratory Instrumentation
Stock Index 40% 7% 7%
Process/Metrology/Motion
Instrumentation 36% 7% 8%
Lab Consumables/Equipment
Stock Index 67% 9% 3%
Diversified Instrumentation
Stock Index 53% 17% 7
Dow Jones Industrial Average
S&P 500
NASDAQ Composite
Region Market Value Market Value
Company (US $000s) (Local $000s)
Pacific Shares
Hitachi High-Technologies: t $2,652,690 [yen] 290,628 720
Horiba: t $918,791 [yen] 100,662,792
JEOL: t $322,863 [yen] 35,372,881
Shimadzu: t $2,680,547 293,680,743
Techcomp: si $60,823 SGD 42,878
European Shares
Genetix: l $629 34,420 [pounds
Millbrook Scientific sterling]
Instruments: l $16 901 [pounds
sterling]
Oxford Instruments: l $2,001 109,575 [pounds
sterling]
Renishaw: l $10,543 577,213 [pounds
sterling]
Robotic Technology Systems: l $44 2,400 [pounds
sterling]
Spectris: 1 $16,233 888,745 [pounds
sterling]
Alpha MOS: c $14,803 10,081 [euro]
Analytik Jena: g $45,165 30,757 [euro]
Biohit: h $25,457 17,336 [euro]
Cybio: g $8,345 5,683 [euro]
Sartorius: g $513,164 349,465 [euro]
Tecan: s $606,174 CHF 666,427
Biotage: st $1,144 SEK 7,344
Exiqon: no $143,410 DKK 728,235
Price
Region 6/30/2008 Change Change
Company (Local) 1 Month YTD
Pacific Shares
Hitachi High-Technologies: t [yen] 2030 -4% -17%
Horiba: t [yen] 2175 -8% -47%
JEOL: t [yen] 395 -11% -17%
Shimadzu: t [yen] 1031 4% 3%
Techcomp: si $0.40 -8% -17%
European Shares
Genetix: l 0.55 [pounds 14% 6%
Millbrook Scientific sterling]
Instruments: l 0.02 [pounds 55% -8%
sterling]
Oxford Instruments: l 2.24 [pounds -1% 13%
sterling]
Renishaw: l 8.39 [pounds 6% 34%
sterling]
Robotic Technology Systems: l 0.05 [pounds 26% -50%
sterling]
Spectris: 1 8.31 [pounds 16% 22%
sterling]
Alpha MOS: c 3.82 [euro] -1% -4%
Analytik Jena: g 7.06 [euro] 8% 5%
Biohit: h 1.50 [euro] 12% -4%
Cybio: g 1.65 [euro] 46% -60%
Sartorius: g 19.30 [euro] -6% -29%
Tecan: s CHF 62.9 10% -8%
Biotage: st SEK 8.1 -2% -6%
Exiqon: no DKK 27.5 -8% -27%
Region EPS EPS
Company P/E 12 Month FY
Pacific Shares
Hitachi High-Technologies: t 13 [yen] 152.87 [yen] 195.80
Horiba: t 12 [yen] 187.93 [yen] 204.39
JEOL: t 11 [yen] 35.50 [yen] 35.50
Shimadzu: t 27 [yen] 37.53 [yen] 37.53
Techcomp: si 9 $0.04 $0.04
European Shares
Genetix: l 16 0.03 [pounds 0.03 [pounds
Millbrook Scientific sterling] sterling]
Instruments: l N/A 0.00 [pounds 0.00 [pounds
sterling] sterling]
Oxford Instruments: l 41 0.06 [pounds 0.06 [pounds
sterling] sterling]
Renishaw: l 18 0.48 [pounds 0.48 [pounds
sterling] sterling]
Robotic Technology Systems: l N/A -0.06 [pounds -0.06 [pounds
sterling] sterling]
Spectris: 1 14 0.61 [pounds 0.71 [pounds
sterling] sterling]
Alpha MOS: c N/A -0.14 [euro] 0.14 [euro]
Analytik Jena: g 15 0.47 [euro] 0.40 [euro]
Biohit: h N/A -0.09 [euro] 0.12 [euro]
Cybio: g N/A -0.91 [euro] -0.91 [euro]
Sartorius: g 11 1.68 [euro] 1.78 [euro]
Tecan: s 14 CHF 4.37 CHF 4.54
Biotage: st 9 SEK 0.85 SEK 1.12
Exiqon: no N/A -DKK 3.95 -DKK 3.35
Region LTD/ FY R&D/
Company Equity ROE Sales
Pacific Shares
Hitachi High-Technologies: t 11% 11% 2%
Horiba: t 21% 11% 7%
JEOL: t 73% 9% 6%
Shimadzu: t 26% 9% 3%
Techcomp: si 4% 17% 1%
European Shares
Genetix: l 7% 6% 8%
Millbrook Scientific
Instruments: l 0% 0% 12%
Oxford Instruments: l 87% 4% 7%
Renishaw: l 16% 21% 18%
Robotic Technology Systems: l 9% N/A N/A
Spectris: 1 46% 28% 9%
Alpha MOS: c 11% N/A N/A
Analytik Jena: g 47% 6% 8%
Biohit: h 76% N/A 6%
Cybio: g 12% N/A 7%
Sartorius: g 52% 9% 7%
Tecan: s 30% 26% 10%
Biotage: st 5% 12% 12%
Exiqon: no 1% N/A 59%
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