US doctors kill skin cancer with cloned T-cells

WASHINGTON (AFP) — US doctors have for the first time successfully treated a skin cancer patient with cells cloned from his own immune system, a study released Wednesday showed.

The ground-breaking treatment for advanced melanoma, or skin cancer, led to a long remission for the patient and used his own cloned infection-fighting T-cells, said doctor Cassian Yee, the lead author of the study in the New England Journal of Medicine.

Yee and his associates from the Clinical Research Division at Fred Hutchinson Cancer Research Center in Seattle removed CD4+ T-cells, a type of white blood cell, from a 52-year-old man whose melanoma had spread to a groin lymph node and to one of his lungs.

The melanoma was already well advanced and in stage four.

The T-cells which specifically fight melanoma were modified and expanded in the laboratory and some five billion cells were ...