Cholesterol Drug Controversy Continues
HealthDay, March, 2008 by Ed Edelson, HealthDay Reporter
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A divided cardiology community is trying once again to make sense of a trial showing that a drug can lower levels of "bad" LDL cholesterol and yet give no apparent benefit to people at high risk of heart attack and other cardiovascular problems.
simvastatin -- with ezetimibe, which also lowers LDL cholesterol, but in a different way. A controversy erupted earlier this year when Merck/Schering-Plough, which markets the drug in the United States, released results of a European trial that showed the combined medication did not reduce buildup of potentially artery-blocking plaque deposits any more than simvastatin alone.
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Those results and their implications were discussed Sunday at the American College of Cardiology annual meeting, in Chicago. The New England Journal of Medicine , which will publish two papers and two editorials on the drug in its April 3 issue, released the papers early to coincide with the meeting.
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