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Industry: Email Alert RSS FeedCephalosporins can be prescribed safely for penicillin-allergic patients
Journal of Family Practice, Feb, 2006 by Michael E. Pichichero
(47.) James J. Diagnosis of penicillin, amoxicillin, and cephalosporin allergy: reliability of examination assessed by skin testing and oral challenge. Pediatrics 1999; 104:367.
(48.) Pichichero M, Pichichero D. Diagnosis of penicillin, amoxicillin, and cephalosporin allergy: Reliability of examination assessed by skin testing and oral challenge. J Pediatr 1998; 132:137-143.
(49.) Romano A, Mayorga C, Torres M, et al. Immediate allergic reactions to cephalosporins: Cross-reactivity and selective responses. J Allergy Clin Immunol 2000; 106:1177-1183.
(50.) Salkind A, Cuddy P, Foxworth J. Is this patient allergic to penicillin? An evidence-based analysis of the likelihood of penicillin allergy. JAMA 2001; 285:2498-2505.
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(51.) Smith J, Johnson J, Cluff L. Studies on the epidemiology of adverse drug reactions: II. An evaluation of penicillin allergy. N Engl J Med 1966; 274:998-1002.
(52.) Warrington R, Simons F, Ho H, et al. Diagnosis of penicillin allergy by skin testing: the Manitoba experience. Can Med Assoc J 1978; 118:797-791.
(53.) Saxon A, Beall G, Rohr A. immediate hypersensitivity reactions to beta-lactam antibiotics. Ann Intern Med 1987; 107:204-215.
FAST TRACK Penicillin compounds contaminated with cephalosporins led to the erroneous assumption of 10% cross-reactivity
FAST TRACK Help patients reconstruct the "allergic" episode to rule out non-immunologic adverse events that do not contraindicate cephalosporins
FAST TRACK Even for patients truly allergic to penicillin, the risk of a reaction from a cephalosporin with a different side chain is quite low
Michael E. Pichichero, MD University of Rochester Medical Center, Rochester, NY
CORRESPONDENCE
Michael E. Pichichero, MD, University of Rochester Medical Center, 601 Elmwood Avenue, Box 672, Rochester, New York 14642. E-mail: Michael_pichichero@urmc.rochester.edu
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