Does warfarin prevent deep venous thrombosis in high-risk patients?

Journal of Family Practice, March, 2004 by Rebecca L. Spaulding, M. Lee Chambliss, Leslie Mackler

John P. Langlois, MD, MAHEC Family Practice Residency, Asheville, NC

REFERENCES

(1.) Ridker PM, Goldhaber SZ, Danielson E, et al. Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med 2003; 348:1425-1434.

(2.) Kearon C, Ginsberg JS, Kovacs MJ, et al. Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med 2003; 349:631-639.

(3.) Pinede L, Duhaut P, Cucherat M, Ninet J, Pasquier J, Boissel JP. Comparison of long versus short duration of anticoagulant therapy after a first episode of venous thromboembolism: a meta-analysis of randomized, controlled trials. J Intern Med 2000; 247:553-562.

(4.) Kearon C, Gent M, Hirsh J, et al. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. N Engl J Med 1999; 340:901-907.

(5.) Agnelli G, Prandoni P, Santamaria MG, et al. Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis. Warfarin Optimal Duration Italian Trial Investigators. N Engl J Med 2001; 345:165-169.

(6.) Levine M, Hirsh J, Gent M, et al. Double-blind randomised trial of a very-low-dose warfarin for prevention of thromboembolism in stage IV breast cancer. Lancet 1994; 343:886-889.

(7.) Rajan R, Gafni A, Levine M, Hirsh J, Gent M. Very low-dose warfarin prophylaxis to prevent thromboembolism in women with metastatic breast cancer receiving chemotherapy: an economic evaluation. J Clin Oncol 1995; 13:42-46.

(8.) Ginsberg JS, Bates SM, 0czkowski W, et al. Low-dose warfarin in rehabilitating stroke survivors. Thromb Res 2002; 107:287-290.

(9.) Hirsh J, Dalen J, Guyatt G; American College of Chest Physicians. The sixth (2000) ACCP guidelines for antithrombotic therapy for prevention and treatment of thrombosis. American College of Chest Physicians. Chest 2001; 119(1 Suppl):132S-193S.

Rebecca L. Spaulding, MD, M. Lee Chambliss, MD, MSPH, Moses Cone Family Medicine Residency, Greensboro NC; Leslie Mackler, MLS, Moses Cone Health System, Greensboro NC

COPYRIGHT 2004 Dowden Health Media, Inc.
COPYRIGHT 2004 Gale Group
 

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