The Linus Pauling - Mayo Clinic controversy involving vitamin C and cancer tests

Nutrition Health Review, Wntr, 1995 by Steve Austin, Cathy Hitchcock

(1.)Pavelic, K. L-ascorbic acid-induced DNA strand breaks and cross links in human neuroblastoma cells, Brain Res 1985; 342:369-73.

(2.)Morrison, D.G. et al. Retinyl palmitate and ascrobic acid inhibit pulmonary neoplasms in mice exposed to fiberglass dust. Nutr Cancer 1982; 3(2):81.

(3.)Abdel-Galili, A.M. Preventive effect of vitamin C (L-ascrobic acid) on methylcholanthrene-induced soft tissue sarcomas in mice. Oncology 1986; 43:335-7.

(4.)Weisburger, J.H. Vitamin C, vitamin E, and the prevention of gastric cancer: discussion. Ann NY Acad Sci 1980; 355:278-9.

(5.)Tannenbaum, W., and W. Mergens. Reaction of nitrite with vitamins C and E. Ann NY Acad Sci 1980; 355:267-75.

(6.)Weisburger, J.H. Causes of gastric and esophageal cancer. Possible approaches to prevention of vitamin C. Int J Vit Nutr Res 1985; Suppl #27:381-402.

(7.)Block, G. Vitamin C and cancer prevention: the epidemilogic evidence. Am J Clin Nutr 1991; 53:270S-82S [review].

(8.)Basu, T.K. The significance of ascorbic acid, thiamin, and retinol in cancer. Int J Vit Nutr Res 1983; Suppl #24:105-17.

(9.)Hanck, A. Vitamin C and cancer. Int J Vit Nutr Res 1983; Suppl #24:87-104.

(10.)Cameron, E., and L. Pauling. Supplemental ascorbate in the supportive treatment of cancer: prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA 1976; 73:3685-9.

(11.)Cameron, E., and L. Pauling. Supplemental ascorbate in the supportive treatment of cancer: reevaluation of prolongation of survival times in terminal human cancer. Proc Natl Acad Sci USA 1978; 75:4538-42.

(12.)Moertel, C.G. A proposition: megadoses of vitamin C are valuable in the treatment of cancer -- negative. Nutr Rev 1986; 44(1):29-30.

(13.)Creagan, E.T., et al. Failure of high dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. N Engl Med 1979; 301:687-90.

(14.)Moertel, C.G., et al. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy: a randomized double-blind comparison. New Engl J Med 1985; 312(3):137-41.

(15.)Moertel, C.G., et al. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy: a randomized double-blind comparison. New Engl J Med 1985; 312(3)137-41.

(16.)The effects of high dose vitamin C on survival of cancer patients. Int Clin Nutr Rev 1985; 5(4):163-5 [editorial].

(17.)Chaitow, L. Vitamin C study on cancer patients "seriously flawed." J Alternative Med April 1985, pp. 18-19.

(18.)Moertel, C.G., et al. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy: a randomized double-blind comparison. New Engl J Med 1985; 312(3)137-41.

(19.)The effects of high dose vitamin C on survival of cancer patients. Int Clin Nutr Rev 1985; 5(4):163-5 [editorial].

(20.)Murata, A., F Morishige, and H. Yamaguchi. Prolongation of survival times of terminal cancer patients by administration of large doses of ascorbate. Int J Vit Nutr Res 1982; Suppl #23:103-114.