Occupational Health and Safety Report Provides Ready to Use Protocols for Human Biomonitoring Methods

Business Wire,  Nov 26, 2007  

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DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c75222) has announced the addition of "The MAK Collection for Occupational Health and Safety: Part IV: Biomonitoring Methods, Volume 11" to their offering.

Detailed, ready-to-use protocols for human biomonitoring methods, are provided here, which were developed to monitor concentrations of occupational toxicants, yet can be equally used for environmental monitoring. Examples are new methods for the determination of organophosphates or musk compounds in blood. All the methods are reliable, reproducible, adhere to 'Good Laboratory Practice' standards and cover all the required steps from sampling to the interpretation of results with respect to relevant biological exposure values. This includes data on precision, accuracy, and detection limit, calibration procedures as well as potential sources of systematic errors.

Author Information

Jurgen Angerer is Head of the working group "Analytical Chemistry" of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. He is a member of the International Society of Exposure Analysis (ISEA) and board member of the International Society of Environmental Medicine (ISEM). He is author and editor of numerous books and belongs to the editorial boards of the Journal of Chromatography B as well as of the International Journal of Hygiene and Environmental Health.

Helmut Greim is Head of the Scientific Committee for Occupational Exposure Limits (SCOEL), which is working for the European Commission, and the former Head of the DFG-Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area.

High-Performance Liquid Chromatography/Mass Spectrometry (LC/MS)

Determination of Neurotoxic Esterase Activity in Leucocytes

2,3,7,8-Tetrachlorodibenzodioxin (TCDD) in Blood

Bisphenol A in Urine

Organophosphates (Chlorpyrifos, Diazinon, Fenitrothion, Fenthion und Malathion) in Blood

Musk Compounds (4-Acetyl-1,1-dimethyl-6-tert.-butydihydroinden;

6-Acetyl-1,1,2,3,3,5-hexamethyl-dihydroinden;

1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-[g] -2-benzopyran;

7-Acetyl-1,1,3,4,4,6-hexamethyl-tetralin) in Blood

Urine Metabolites of 1,3-Butadien (Monohydroxybutenyl-Mercapturic Acid and Dihydroxybutyl- Mercapturic Acid)

Urine Metabolites of N-Methyl-2-pyrrolidon (5-Hydroxy-N-methyl-2-pyrrolidon und 2-Hydroxy-N-methylsuccinimid)

Palladium in Urine

Urine Metabolites of Glycol Ether and Glycol Ether Acetate (1-Methoxy-2-propanol, 1-Ethoxy-2-propanol, 1-Propoxy-2-propanol, 1-Butoxy-2-propanol, 1-Phenoxy-2-propanol)

Iridium in Urine

Urine Metabolites of Di(2-ethylhexyphthalate) (2-Ethyl-5-hydroxyhexylphthalate, 2-Ethyl-5-oxohexylphthalate and Mono(2-ethylhexyl)phthalate)

For more information visit http://www.researchandmarkets.com/reports/c75222

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