ArQule, Inc. to Present at BMO Capital Markets Focus on Healthcare Conference

Business Wire, July 29, 2008

WOBURN, Mass. -- ArQule, Inc. (Nasdaq: ARQL) today announced that it will present at the BMO Capital Markets Focus on Healthcare Conference on Tuesday, August 5, 2008 at 10:45 a.m. eastern time.

ArQule's presentation will be web cast live and can be accessed through the investor relations section of the Company's website, www.arqule.com. The conference will be held at the Millennium Broadway Hotel, New York.

About ArQule

ArQule is a biotechnology company engaged in the research and development of next-generation, small-molecule cancer therapeutics. The Company's targeted, broad-spectrum products and research programs are focused on key biological processes that are central to cancer. ArQule's lead products, which are in clinical-stage development, consist of ARQ 197, an inhibitor of the c-Met receptor tyrosine kinase, and ARQ 501, an activator of the cell's DNA damage response mechanism mediated by the E2F-1 transcription factor. The Company's most advanced pre-clinical development programs are focused on ARQ 761, a second-generation E2F-1 product candidate, as well as compounds that inhibit the Eg5 kinesin spindle protein and the BRAF kinase. ArQule's discovery efforts are focused on the identification of novel kinase inhibitors that are potent, selective and do not compete with ATP (adenosine triphosphate), an energy source for cells. For more information, please visit www.arqule.com.