ZymoGenetics to Webcast Presentation at Piper Jaffray London Conference

Business Wire, June 18, 2008

SEATTLE -- ZymoGenetics, Inc. (NASDAQ:ZGEN) announced today that Douglas E. Williams, Ph.D., President and Chief Scientific Officer, will provide an update on company activities at the Piper Jaffray Third Annual Europe Conference in London on Wednesday, June 25, 2008 at 11:20 a.m. British Summer Time (6:20 a.m. Eastern Daylight Time).

A live webcast of the presentation can be accessed by going to: www.zymogenetics.com. The webcast will be archived for 30 days.

About ZymoGenetics

ZymoGenetics creates novel protein drugs with the potential to significantly help patients fight their diseases. The Company is developing a diverse pipeline of proprietary product candidates that are moving into and through clinical development. These candidates span a wide array of clinical opportunities that include bleeding, autoimmune and viral diseases and cancer. ZymoGenetics intends to commercialize these product candidates through internal development, collaborations with partners, and out-licensing of patents from its extensive patent portfolio. For further information, visit www.zymogenetics.com.

This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on the current intent and expectations of the management of ZymoGenetics. These statements are not guarantees of future actions and involve uncertainties that are difficult to predict. Except as required by law, ZymoGenetics undertakes no obligation to update any forward-looking or other statements in this press release, whether as a result of new information, future events or otherwise.