Identify Which Targeting Strategies Are At Work Within Antiangiogenic Drug Developments

Business Wire,  March 25, 2008  

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DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c86665) has announced the addition of "Target Atlas: Competitive Insights to Anti-Angiogenic Drug R&D in Oncology" to their offering.

There is a plethora of new anti-angiogenic drugs in development. The potential to block tumour growth and metastases by angiogenesis inhibition represents an intriguing therapeutic strategy for the treatment of cancer and never before have we seen as many anti-angiogenic drugs in clinical trials.

This report is written for you to identify your competition and understand which targeting strategies are at work within anti-angiogenic drug development in oncology. It allows you to pin-point which competitors drugs' clinical out-come may have bearing on your own drug development and who are developing sequels to blockbuster drugs. This report also helps you to locate white-spots in the competitive landscape, giving you little or no competition. Conversely it may reveal unexpected competition for you.

First, the author surveyed anti-angiogenic drugs in oncology and identified 108 drug targets, belonging to 123 drugs. This report, Target Atlas: Competitive Insights to Anti-Angiogenic Drug Ramp;D in Oncology, is an open landscape of resources to build, fuel, and drive your scientific competitive vehicle for the advancement of new anti-angiogenic drugs in oncology.

In the report, the author reports on 88 unique drug target combinations, each comprised of a different collection or mix of individually defined targets, for 123 anti-angiogenic drugs designed for the treatment of 44 different cancer indications. The highest degree of distinctiveness among anti-angiogenic drugs is achieved by sorting each of them according to targeted cancer indication, drug target mix, and drug compound type. At the same time we are also identifying peer groups of drugs, that is, drugs we consider suitable for head-to-head comparison during drug development.

To fuel the scientific and competitive thinking, the author opens the gate into the presence and relevance of protein-protein interactions between identified targets of anti-angiogenic drugs. No less than 162 protein-protein interactions were recognized among and between 86 of the 108 included anti-angiogenic drug targets.

Why You Should Own Your Own Copy of this Report:

* 230+ pages, with almost a hundred different tables and figures. Includes more than 1,500 active links to related resources on the Internet

* 123 anti-angiogenic drugs, under development by 90 investigators, are included, covering more than 361 developmental projects in cancer

* 108 Unique, in-depth, drug target profiles, highlighting twelve themes about the drug target, i.e. protein-protein interaction with other anti-angiogenic drug targets, linked cancer indications, drugs under development, compound types, presence in the Cancer Genome Project etc.

* Unique 231 drug-protein target interactome analysis

* Unique drug target combination breakdown into 44 different cancer types

* Covers 88 unique drug target combinations of anti-angiogenic drugs

* 162 protein-protein interactions among and between anti-angiogenic drug targets

* Pathway grouping of anti-angiogenic drug targets

* Pin-point which competitor drugs' clinical out-come may have bearing on your own drug development

* Who are working on sequels to blockbuster drugs

* Locate white-spots in the competitive landscape, giving you little or no competition

In all, this report is a serious reference for any professional interested in the development of oncology drug targets and the selection/validation of targeting strategies.

Contents:

1 Executive Summary

2 About Cancer Highlights

3 Methodologies

4 Table of Contents

5 How to Use this Report

6 Anti-Angiogenic Drug Compound Types and Sub-cellular Localizations of Targets

7 The Cancer Genome Project and Angiogenesis Drug Targets

8 Protein Expression Profiles of Anti-Angiogenic Drug Targets in Human

9 Pathway Analysis of Anti-Angiogenic Drugs

10 Protein-Protein Interactions Among Identified Anti-Angiogenic Drug Targets

11 Available Biological Structure Data on Anti-Angiogenic Drug Targets

12 Drug Target Profiles of Anti-angiogenesis Drug Targets in Oncology

13 The Drug-Protein Interactome of Anti-Angiogenic Drugs

14 The Progression and Maturity of Anti-Angiogenic Drug Target Combinations

15 Anti-Angiogenic Drug Target Mix by Cancer Indication

16 Anti-Angiogenic Drugs and Their Targets by Companies

16.1 Australia

16.2 Austria

16.3 Belgium

16.4 Canada

16.5 China

16.6 Denmark

16.7 France

16.8 Germany

16.9 Israel

16.10 Japan

16.11 Netherlands

16.12 South Korea

16.13 Spain

16.14 Sweden

16.15 Switzerland

16.16 United Kingdom

16.17 USA

17 Disclaimer

18 Drug Index

19 Company Index

List of Figures

List of Tables

For more information visit http://www.researchandmarkets.com/reports/c86665

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