Latest Statistics and Forecasts Regarding the Sleep Disorders Market: Insomnia, Sleep Apnea, Restless Leg Syndrome, Bruxism, Narcolepsy and Sleepwalking

Business Wire, March 03, 2009

Table App 4.1: Sample BMIs for Weight and Height Ranges 262

Table App 4.2: U.S. Obesity Rates, 2007 262

Table App 4.3: Demographic Statistics of a Pediatric Surgical Population in the U.S. 267

Table App 5.1: Physiological Changes during NREM and REM Sleep 272

Table App 5.2: Percent Sleep for Young Children 274

Table App 5.3: Percent Sleep for Young Adults 275

Table App 5.4: Percent Sleep for Elderly Adults 275

Table App 6.1: Current Sleep Related Clinical Trials 278

Table App 6.2: Just Completed and On-going Clinical Trials for Circadian Rhythm Sleep Disorders 278

INDEX OF FIGURES

Figure 1.1: Total market for Leading Sleep Drugs, 2007 17

Figure 1.2: Sleep Product's Market Share in 2007 17

Figure 1.3: Percent Market Share of Leading CPAP Devices, 2008 18

Figure 1.4: U.S. Rx and OTC Sleeping Pills market, 2003-2007 18

Figure 1.5: U.S., CPAP Sleep Apnea Devices market, 2003-2007 19

Figure 1.6: U.S. Mattresses and Foundations Retail Market, 2003-2008 20

Figure 1.7: U.S. Sleep Lab Revenues, 2003-2007 20

Figure 1.8: Number of Accredited Sleep labs in the U.S., 2003-2007 21

Figure 1.9: Projected U.S. Growth of Sleep Center Beds in 2009 21

Figure 1.10: Circadin's Effect on the Improvement in Quality of Sleep 24

Figure 2.1: Hours of Sleep in a Sample U.S. Population, 2008 27

Figure 2.2: Person Wearing Electrodes for EGG 29

Figure 2.3: Portable Recording Device for EEG 29

Figure 2.4: Treatment Effects on Patients with Hypersomnia 33

Figure 2.5: Adults with Sleep Apnea Symptoms who Sought Medical Care in the U.S., 2006 34

Figure 2.6: Open Throat 36

Figure 2.7: Closed Throat in an Apnea Patient 36

Figure 2.8: mandibular Advancement Device (MAD) for Sleep Apnea 37

Figure 2.9: Continuous Positive Airway Pressure (CPAP) Treatment 38

Figure 2.10: Sleep Apnea Percentage by Medical Specialty as Reported by NAMCS 41

Figure 2.11: NAMCS Ages of Sleep Apnea Patients 41

Figure 2.12: Age-specific Prevalence of Obstructive Sleep Apnea Diagnosed 43

Figure 2.13: Prevalence of Sleep Aid use by Age Group in the U.S., 1998-2006 45

Figure 2.14: Percentage of Sleep Aid Users Younger Than 45 Years old in the U.S., 1998-2006 46

Figure 2.15: Prevalence of mental health Diagnosis Made in First Sleep Aid Users by Provider Type 47

Figure 2.16: Common Symptoms of Insomnia 48

Figure 2.17: Insomnia Patient Population, 2007 49

Figure 2.18: Obesity Prevalence by Age and Sex in the U.S., 2005-2006 50

Figure 2.19: Prevalence of Obesity in U.S. Women by Age and Race/Ethnicity, 2005-2006 50

Figure 2.20: The Globally Growing Market for Insomnia, 2001-2006 53

Figure 2.21: Global Prescription for Insomnia Products, 2001-2006 53

Figure 2.22: Global Sales of Insomnia Drugs, 2007 54

Figure 2.23: Projected Global Insomnia Market, 2005-2009 55

Figure 2.24: Frequency of Insomnia Symptoms in the U.S. Adult Population 55

Figure 2.25: U.S. Sleep market - Under Penetrated 56

Figure 2.26: Projected U.S. Sleep Market Growth in 2009 57

Figure 2.27: Time to Sleep for RLS Sufferers 62

Figure 2.28: Times RLS Sufferers Woken at Night 63