deCODE and Celera Partner to Expand Use of deCODE Risk Markers for Heart Attack, Stroke and Diabetes

Business Wire, April 23, 2009

Selected references

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2. Brautbar, A, et al., “Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities (ARIC) study. Circulation: Cardiovascular Genetics (2009). Published online ahead of print, April 21, 2009.

3. Gudbjartsson, D.F., et al., “Variants conferring risk of atrial fibrillation on chromosome 4q25,” Nature (2007) 448:353-57; Gulcher J, Gretarsdottir S, Thorleifsson G, et al., Abstract 1171: “Risk variants for atrial fibrillation on chromosome 4q25 associate with non-cardiogenic stroke suggesting that AF is a much greater cause of stroke than previously recognized,” Circulation (2008);118:S_652.

4. Grant, et. al., "Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes," Nature Genetics (2006) 38, 320 - 323; Florez, et. al., "TCF7L2 Polymorphisms and Progression to Diabetes in the Diabetes Prevention Program," N Engl J Med (2006); 355:241-250.