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Study investigates new medication to treat septic shock - Brief Article

Six research centers will participate in a national study to evaluate the effectiveness of an investigative medication to treat patients with septic shock, according to a July 24, 2003, news release from the Saint Louis University School of Medicine, St Louis. Sepsis is the body's inflammatory response to infection. Uncontrolled inflammation causes life-threatening decreases in blood pressure (ie, shock) and organ damage. Septic shock is a leading cause of death in hospitals, and three out of 10 patients with severe infections die of shock even though they are receiving antibiotics.

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The study will examine the effects of an investigational medication intended to restore blood pressure and improve blood flow and oxygen delivery for patients experiencing shock by removing substances that abnormally dilate blood vessels and cause blood pressure to drop. Researchers will evaluate how the medication affects patients' lungs and whether it allows major organs to receive sufficient blood supply and oxygen to function properly. They also will study the medication's effects on mechanical ventilation and patients' length of stay in the intensive care unit and hospital.

SLU Researches Medication to Treat Life-Threatening Complication of Sepsis (news release, St Louis: Saint Louis University School of Medicine, July 24, 2003) http://www.stu.edu/readstory/newsinfo/2913 (accessed 1 Aug 2003).

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Study investigates new medication to treat septic shock - Brief Article

AORN Journal, Oct, 2003

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