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Daily aspirin dose may help prevent prostate cancer - Patient Safety First - Brief Article - Statistical Data Included

Men who take aspirin, ibuprofen, or other non-steroidal anti-inflammatory medications (NSAIDs) daily may reduce their risk of developing prostate cancer, the second leading cause of cancer death among men in the United States, according to a March 11, 2002, news release from the Mayo Clinic Rochester. Of 1,362 Caucasian men who participated in a study for an average of five and one-half years, 23 (4%) of the 569 who reported using NSAIDs daily developed prostate cancer. Of the 793 men who did not use NSAIDs daily, 68 (9%) developed the disease.

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Researchers also found that the association between NSAID use and decreased risk of prostate cancer appears to be stronger in older men. The incidence of prostate cancer for men 50 to 59 years of age was 12% lower among those using NSAIDs daily compared to those who did not use NSAIDs daily. Among men 60 to 90 years of age, the risk was 60% lower, and among those 70 to 79 years of age, the risk was 83% lower.

The study findings complement previous studies that indicate NSAID use can help protect against breast and colon cancers. Researchers caution, however, that the findings of this study are not conclusive. Further research is needed to determine whether the results can be confirmed by similar studies and whether the findings are applicable to men of other races. In addition, researchers need to determine the optimum dosage and duration to provide protection against prostate cancer and better understand the biological association between the use of NSAIDs and prostate cancer. Men should follow their physician's advice regarding taking NSAIDs daily.

Could an Aspirin a Day Help Keep Prostate Cancer Away?. Possibly (news release, Rochester, Minn: Mayo Clinic Rochester, March I 1, 2002) http//www.moyo.edu/comm/mcr/news_2018.html (accessed 4 April 2002).

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Daily aspirin dose may help prevent prostate cancer - Patient Safety First - Brief Article - Statistical Data Included

AORN Journal, June, 2002

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