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Industry: Email Alert RSS FeedChronic fatigue, aging, mitochondrial function and nutritional supplements
Townsend Letter for Doctors and Patients, July, 2003 by Garth L. Nicolson
(23.) Kagan T, Davis C, Lin L, Zakeri Z. Coenzyme Q10 can in same circumstances block apaptosis, and this effect is mediated through mitochondria. Ann NY Acad Sri 1999; 887:31-47.
(24.) Matthews RT, Yang L, Browne S, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Aced Sci USA 1998; 95: 8892-8897.
(25.) Miquel, J. Can antioxidant diet supplementation protect against age-related mitochondrial damage? Ann NY Acad Sci 2002; 959:317-347.
(26.) Hu HL, Forsey RJ, Blades RJ. Darratt ME, Parmar P, Powell JR. Antioxidants may contribute in the fight against ageing: an in vitro model. Mech Ageing Dev 2000; 121: 217-230.
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(27.) Passi S, De Pita O, Puddu P. Littarru GP. Lipophilic antioxidants in human sebum and aging. Free Radical Res 2002; 36: 471-477.
(28.) Forsyth LM, Preuss HG, MacDowell AL, et al. Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome. Ann Allergy Asthma Immunol 1999; 82: 185-191.
(29.) Seidman M, Khan MJ, Tang WX, Quirk WS. Influence of lecithin en mitochondrial DNA and age-related hearing loss. Otolaryngol Head Neck Burg 2002; 127:138.144.
(30.) Kim MJ, Cooper DD, Hayes SF, Spangrude GJ. Rhodamine-123 staining in hematopoietic stem cells of young mice indicates mitochondrial activation rather than dye efflux. Bleed 1998; 91:4106-4117.
(31.) Colodny L, Lynch K, Farber C, Papish S, et al. Results of a study to evaluate the use of Propax to reduce adveree effects of chemotherapy. JANA 2000; 2: 17-25.
(32.) Paradies G, Petrosillo G, Pistolese M, Ruggiero F. Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage. Gene 2002; 286:135-141.
(33.) Kowald A. The mitochondrial theory of aging: do damaged mitochondria accumulate by delayed degradation? Exp Gerontol 1999; 34:605-612.
(34.) Kobaska J, Coskun P, Esposito L, Wallace DC. Increased mitochondrial oxidative stress in the Sod2( /-) mouse results in age-related decline of mitochondrial function culminating in increased apoptosia. Proc Nat Acad Sri USA 2091;98:2278-2283.
(35.) Johns DR, 1995. Seminars in medicine of Beth Israel Hospital, Boston: Mitochondrial DNA and Disease. N Engl J Med. 1995; 333: 638-44.
Correspondence:
Prof. Garth L. Nicolson, PhD
The Institute for Molecular Medicine 15162 Triton Lane
Huntington Beach, California 92649 USA 714-903-2901 / Fax 714-379-2082
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