The genomeceutical effect of probiotics and their potential role in quenching autoimmune diseases and disorders of inflammation

Townsend Letter for Doctors and Patients, May, 2004 by Mark A. Brudnak, Llori M. Valenzuela

9. Rachmilewitz D, Katakura K, Karmeli F, Hayashi T, Reinus C, Rudensky B, Akira S, Takeda K, Lee J, Takabayashi K, Raz E. 2004. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology. Feb;126(2):520-8.

10. Gill HS, Rutherfurd KJ, Prasad J, and Gopal PK. 2000. Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019). Brit J Nutr. 83:167-76.

11. Vanderhoof J and Young R. 2003. Role of probiotics in the management of patients with food allergy. Ann Allergy Asthma Immunol. Jun;90(6 Suppl 3):99-103.

12. Majamaa H, Isolauri E. 1997. Probiotics: a novel approach in the management of food allergy. L Allergy Clin Immunol. Feb;99(2):-179-85.

13. Dalloul RA, Lillehoj HS, Shellem TA, Doerr JA. 2003. Intestinal immunomodulation by viamin A deficiency and lactobacillus-based probiotic in Eimeria acervulina-infected broiler chickens. Auian Dis. Oct-Dec;47(4):1313-20.

14. Hirano J, Yoshida T, Sugiyama T, Naoki K, Mori I, Yokochi T. 2003. The effect of Lactobacillus rhamnosus on enterohemorrhagic Eshcerichia coli infection of human intestinal cells in vitro. Microbiol Immunol. 47(6):405-9.

15. Majamaa H, Isolauri E, Saxelin M, Vesikari T. 1995. Lactic acid bacteria in the treatment of acute rotavirus gastroenteritis. J Pediatr Gastroenterol Nutr. Apr;20(3):333-8.

16. Shu Q, Lin H, Rutherfurd Kj, Fenwick SG, Prasad J, Gopal PK, Gill, HS. 2000. Dietary Bifidobacterium lactis (HN019) enhances resistance to oral Salmonella typhimurium infection in mice. Microbiol Immunol. 44(3):213-22.

17. Brudnak, MA 2001 Nutritional Regulation of Gene Expression. Theory in Biosciences. 1 March, vol. 120, no. 1, pp. 64-75(12).

18. Miller, K.S. and Brudnak, M. (1994) Expression Cloning: PCR Versus Episomal Vectors for Rescue of Transfected Genes. In PCR in Neuroscience (Methods in Neuroscience Vol. 26) Volume Editor G. Sarkar, Academic Press, Orlando, FL.

19. Wentworth P Jr, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA 3rd, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science. 2001 Sep 7;293(5536):1806-11.

20. Brudnak, MA 2002 Natural Weight-loss Supplements: Are Safe Alternatives Available? Positive Health April (75).

21. Brudnak, MA 2002 Probiotics and Cancer. Townsend Letter for Doctors & Patients. June: 62-65.

22. Brudnak, Mark A. (2003) The Probiotic Solution: Nature's Secret to Radiant Health. ISBN: 0-938045-75-X Dragon Door Publications. MN March

by Mark A. Brudnak, PhD, ND and Llori M. Valenzuela, MS, RD

1817 Wisconsin Ave., Suite 140 * Grafton, Wisconsin 53024 USA * Fax 425-962-8342

Mark. Brudnak@alumni.usc.edu