Clobetasol propionate 0.05% lotion in the treatment of moderate to severe atopic dermatitis: a randomized evaluation versus clobetasol propionate emollient cream

Journal of Drugs in Dermatology, May-June, 2005 by Debra Breneman, Alan B. Fleischer, Jr., David Kaplan, Mark Lebwohl, Bruce Miller, David Pariser, Toivo Rist, L. Swinyer, Yin Liu, Valerie Foley

Disclosures: The investigating authors received honoraries for participating in this clinical research project. In addition Dr. Fleischer has project funding from Galderma. Two of the authors are employees of Galderma R & D, Inc. The authors have no other conflict of interest to disclose.

References

1. Rudikoff D, Lebwohl M. Atopic dermatitis. Lancet. 1998;351:1715-1721.

2. Coca AF, Cooke RA. On the classification of the phenomenon of hypersensitiveness. J Immunol. 1923;8:163-182.

3. Oakes RC, Cox AD, Burgdorf WH. Atopic dermatitis. A review of diagnosis, pathogenesis and management. Clin Pediatr. 1983;22(7):467-475.

4. Williams HC, Wuthrich B. The natural history of atopic dermatitis. In: Williams HC (Ed). Atopic Dermatitis. The epidemiology, causes and prevention of atopic eczema. Cambridge University Press, 2000.

5. Leung AK, Barber KA. Managing childhood atopic dermatitis. Adv Ther. 2003; May-Jun; 20(3):129-137.

6. Barnetson RS, Rogers M. Childhood atopic eczema. BMJ. 2002;Jun 8;324:1376-1379.

7. Hanifin JM. Atopic dermatitis in infants and children. Pediatr Clin North Am. 1991 Aug;38(4):769-789.

8. Korting HC, Kerscher MJ, Schafer-Korting M. Topical glucocorticosteroids with improved benefit/risk ratio: do they exist? J Am Acad Dermatol. 1992; Jul; 27(1):87-92.

9. Charman CR, Morris AD, Williams HC. Topical corticosteroid phobia in subjects with atopic eczema. Br J Dermatol. 2000;142:931-936.

10. Olson EA, Cornell RC. Topical clobetasol-17-propionate: review of its clinical efficacy and safety. J Am Acad Dermatol. 1986;15:246-255.

11. Coulson I. Topical steroids for skin disease. Dermatol Pract. 1996; March/April:5-9.

12. Leung DYM, Bieber T. Atopic Dermatitis. Lancet. 2003; Jan;361:150-160.

13. Correale C, Walker C, Murphy L, Craig TJ. Atopic dermatitis: a review of diagnosis and treatment. Am Fam Physician. 1999; Sep 15;60(4):1191-1198.

14. Charman CR, Williams H. The use of corticosteroids and corticosteroid phobia in atopic dermatitis. Clin Dermatol. 2003;21:193-200.

Debra Breneman MD, (a) Alan B. Fleischer Jr. MD, (b) David Kaplan MD, (c) Mark Lebwohl MD, (d) Bruce Miller MD, (e) David Pariser MD, (f) Toivo Rist MD, (g) L. Swinyer MD, (h) Yin Liu PhD, (i) Valerie Foley PharmDi

a. Dermatology Clinical Research Institute in Cincinnati, OH

b. Department of Dermatology of the Wake Forest University School of Medicine in Winston-Salem, NC

c. Overland Park, KS

d. Mount Sinai Medical Center in New York, NY

e. Oregon Medical Research Center in Portland, OR

f. Eastern Virginia Medical School and Virginia Clinical Research in Norfolk, VA

g. Knoxville, TN h. Salt Lake City, UT i. Galderma R & D, Princeton, NJ