Pharma Industry
Industry: Email Alert RSS FeedChemotherapy and total-body irradiation followed by autologous lymphocyte infusion, aldesleukin, and autologous stem cell transplant in treating patients with metastatic melanoma
Journal of Drugs in Dermatology, March, 2008
Sponsored by: National Cancer Institute (NCI). This phase II trial is studying how well chemotherapy and total-body irradiation followed by autologous lymphocyte infusion, aldesleukin, and autologous stem cell transplant work in treating patients with metastatic melanoma.
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Condition Intervention Phase
Nonmelanomatous Drug: aldesleukin Phase II
Skin Cancer Drug: cyclophosphamide
Drug: filgrastim
Drug: fludarabine phosphate
Drug: therapeutic tumor infiltrating
lymphocytes
Procedure: autologous bone marrow
transplantation
Procedure: autologous hematopoietic stem cell
transplantation
Procedure: colony-stimulating factor therapy
Procedure: hematopoietic stem cell
mobilization
Procedure: high-dose chemotherapy
Procedure: interleukin therapy
Procedure: peripheral blood stem cell
transplantation
Procedure: total-body irradiation
Procedure: tumor infiltrating lymphocyte
therapy
Study ID Numbers: CDR0000480141, NCI-06-C-0136, NCI-P6763
ClinicalTrials.gov Identifier: NCT00335127
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