Efficacy study of antiseptic preoperative scrubs in prevention of postoperative wound infections

Journal of Drugs in Dermatology, March, 2008

Sponsored by: Baylor College of Medicine. Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin. Therefore, it is conceivable that application of an optimal antiseptic agent can reduce the rate of surgical wound infections. This trial is to compare the impact of disinfecting the skin with Chloraprep (2% chlorhexidine and 70% isopropyl alcohol) vs. Betadine on the rates of infection of clean-contaminated surgical wounds. The study will also assess the occurrence of adverse effects on the skin from either antiseptic agent and the cost-savings associated with the use of Chloraprep vs Betadine.

Condition                      Intervention         Phase

Postoperative Wound Infection  Drug: ChloraPrep[R]  Phase III

Study ID Numbers: H-14542

ClinicalTrials.gov Identifier: NCT00290290