Comparison of clindamycin/benzoyl peroxide, tretinoin plus clindamycin, and the combination of clindamycin/benzoyl peroxide and tretinoin plus clindamycin in the treatment of acne vulgaris: a randomized, blinded study

Journal of Drugs in Dermatology, Sept-Oct, 2005 by Steven Bowman, Michael Gold, Adnan Nasir, George Vamvakias

In conclusion, results of this randomized, evaluator-blind, multicenter trial indicate that once-daily treatment with clindamycin 1%/benzoyl peroxide 5% gel provides efficacy similar to that of the more complicated regimen of clindamycin 1%/benzoyl peroxide 5% gel tretinoin 0.025% gel clindamycin 1% gel, with better tolerability.

Conflict of Interest/Financial Disclosures: Dr. Gold has received honoraria for speaking on behalf of Dermik Laboratories. Dr. Bowman and Dr. Nasir have nothing to disclose. Mr. Vamvakias is an employee of Dermik Laboratories. This study was supported by Dermik Laboratories.

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Address for Correspondence

Steven Bowman, MD

Tampa Bay Medical Research, Inc.

3251 McMullen Booth Rd, #301

Clearwater, FL 33761

Phone: 727-724-3316

Fax: 727-725-5562

e-mail: sbowman11@aol.com

Steven Bowman MD, (a) Michael Gold MD, (b) Adnan Nasir MD PhD, (c) George Vamvakias (d)

a. Tampa Bay Medical Research, Inc., Clearwater, FL

b. Tennessee Clinical Research Center, Nashville, TN

c. Department of Dermatology, University of North Carolina Chapel Hill, Chapel Hill, NC