Birth Control Pills; Facts to Know

NWHRC Health Center - Birth Control Pills, Dec 13, 2005

Birth control pills (BCPs) are extremely effective at preventing pregnancy if used correctly and consistently. For example, only five in 1,000 women is likely to get pregnant in the first year of use.

The pill works mainly by preventing ovulation or by thickening the mucus surrounding the cervix, which helps block sperm, reduces risk of symptomatic pelvic inflammatory disease, and thin the lining of the uterus so if an egg is fertilized, it would have trouble implanting.

The pill is the most common form of reversible birth control used by women ages 15 to 44. More than 27 million women in the U.S. are currently using BCPs.

According to the National Cancer Institute, the most serious side effect of the pill continues to be an increased risk of cardiovascular disease. This risk is particularly high in certain groups, like women who smoke who are over 35.

You may not know it, but the pill can help your health. For example, birth control pills can improve menstrual problems like heavy bleeding, pelvic cramps and pain, premenstrual syndrome and irregular cycles. They can prevent loss of bone density and reduce the risk of ovarian cysts. Pill use can also protect you from uterine and ovarian cancer.

The Women's Contraceptive and Reproductive Experience (Women's CARE) study indicated that present or past use among both Caucasian and African-American women ages 36 to 64 did not significantly increase the risk of breast cancer.

References

Curtis KM, Chrisman CE, Peterson HB. "Contraception for women in selected circumstances." Obstet Gynecol 2002;99:1100-1112.

"The Emergency Contraception Website." Princeton University Office of Population Research/Association of Reproductive Health Professionals. http://ec.princeton.edu. Last updated August 2005. Date accessed: August 2005.

"Estimates of the Risk of Cardiovascular Death Attributable to Low-Dose Oral Contraceptives in the United States." American Journal of Obstetrics and Gynecology, Vol. 180, pp. 241-249, Jan. 1999

"European evaluation concludes third generation pills are associated with a small increase in risk of venous thromboembolism" British Medical Journal. 323:828. October 13, 2001. http://bmj.bmjjournals.com. Accessed August 2005.

"FDA Approves Seasonale Oral Contraceptive" FDA Talk Paper/Press release. Sept. 5, 2003. http://www.fda.gov. Accessed August 2005.

Marchbanks, P.A, et al. "Oral Contraceptives and the Risk of Breast Cancer" NEJM 2002. Vol. 346:2025-2032, No. 26.

"Oral Contraceptives and Cancer Risk." National Cancer Institute. http://cis.nci.nih.gov. Last updated: Nov. 3, 2003. Accessed August 2005.

"Parity, Oral Contraceptives, and the Risk of Ovarian Cancer among Carriers and Noncarriers of a BRCA1 or BRCA2 Mutation." New England Journal of Medicine 345(4): 235-240. July 26, 2001. http://content.nejm.org Accessed: August 2005.

"Oral Contraceptives-?An Update." Population Reports/The Johns Hopkins School of Public Health, Center for Communication Programs. http://www.infoforhealth.org. Date created: Spring 2000. Accessed August 2005.

"Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives." The Lancet 2001;358:1427-1429.

Schless, J.J. and Farley, T.M.M. Risk of cardiovascular disease in relation to oral contraception use with and without blood-pressure screening. Draft, Feb. 2000. Presented to meeting on Improving Access and Quality of Care in Family Planning: Medical Eligibility Criteria for Contraceptive Use, World Health Organization, Geneva, Mar. 8E10, 2000. 27 p.

"Stroke and Use of Low-Dose Oral Contraceptives in Young Women: A Pooled Analysis of Two US Studies." Stroke/American Heart Association. http://stroke.ahajournals.org. Date created: August 28, 1990. Accessed August 2005.

"Women in the Know." Ortho-McNeil Pharmaceutical, Inc. 2001. http://www.womenintheknow.com

"FDA Takes Action on Plan B: Statement by FDA Commissioner Lester M. Crawford." FDA press release. http://www.fda.gov. Date created: August 26, 2005. Date Accessed August 2005.

"What Is Thrombosis?" INvestigators Against ThromboEmbolism. http://www.inate.org. Date Accessed September 2005

"Pelvic Inflammatory Disease - CDC Fact Sheet." Centers for Disease Control. http://www.cdc.gov. Date reviewed May 2004. Accessed September 2005.

Petitti, DB. "Clinical practice. Combination Estrogen-progestin Oral Contraceptives." N Engl J Med 2003 Oct 9;349(15):1443-50.

"Choosing the Right Birth Control for Your Patients." The American College of Osteopathic Family Physicians. 2004. Available at: http://www.acofp.org. Accessed October 2005.

"Emergency Contraception: History." Contraception Online. July 2004. Available online at http://www.contraceptiononline.org. Accessed October 2005.

Smith, JS et al. Cervical cancer and use of hormonal contraceptives: a systematic review. Lancet 2003 Apr 5;361(9364):1159-67).

Dickinson, BD et al. Drug interactions between oral contraceptives and antibiotics. Obstet Gynecol 2001 Nov;98(5 Pt 1):853-60)

Keywords: birth control pills, the pill, cardiovascular disease, cancer

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