Treatment With WelChol(R) (Colesevelam Hydrochloride) May Lead To Increased LDL Particle Size For Patients With Moderate Hypercholesterolemia
Market Wire, 20050229
*Please see package insert for full prescribing information for WelChol (colesevelam hydrochloride), Benicar, and the GlucoWatch G2 Biographer.
Pravachol(R) is a registered trademark of Bristol-Myers Squibb Co.
References Lamarche B, Lemieux I, Despres JP. The Small, Dense LDL Phenotype and the Risk of Coronary Heart Disease: Epidemiology, Patho-physiology and Therapeutic Aspects. Diabetes Metab. 1999 Sep;25(3):199-211
(2) Isaacsohn J, Jones P. Effect of colesevelam HCL, a Novel Bile Acid Sequestrant, on LDL Particle Size in Patients with Moderate Hypercholesterolemia. European Atherosclerosis Society 73rd Congress 2002.
(3) Lamarche B, Lemieux I, Despres JP. The Small, Dense LDL Phenotype and the Risk of Coronary Heart Disease: Epidemiology, Patho-physiology and Therapeutic Aspects. Diabetes Metab. 1999 Sep;25(3):199-211
(4) Lamarche B et al. Small, Dense Low-Density Lipoprotein Particles as a Predictor of the Risk of Ischemic Heart Disease in Men. Prospective Results From the Quebec Cardiovascular Study. Circulation. 1997;95:69-75
(5)Isaacsohn J, Jones P. Effect of colesevelam HCL, a Novel Bile Acid Sequestrant, on LDL Particle Size in Patients with Moderate Hypercholesterolemia. European Atherosclerosis Society 73rd Congress 2002.
(6) Davidson, Michael et al. Colesevelam Hydrochloride (Cholestagel): A New Potent Bile Acid Sequestrant Associated with a Low Incidence of Gastrointestinal Side Effects. Archives of Internal Medicine. 1999; 159:1893-1900
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