Vanguard Health Systems, Inc. Invites You to Join Its 2008 First Quarter Earnings Conference Call Webcast

Market Wire, October, 2007

In conjunction with Vanguard Health Systems, Inc.'s 2008 First Quarter Earnings press release, you are invited to listen to its conference call that will be broadcast live over the Internet on November 13, 2007 at 11:00 a.m. Eastern time with senior management of Vanguard discussing the operating results.

WHAT:  Vanguard Health Systems, Inc.'s 2008 First Quarter Earnings
       Conference Call on the Web

WHEN:  Tuesday, November 13, 2007 at 11:00 a.m. Eastern time

WHERE:  http://www.vanguardhealth.com  or
        http://www.visualwebcaster.com/event.asp?id=43376 

HOW:   Live over the Internet -- Simply log on to the web at one of
       the addresses above.  If you connect through
        www.vanguardhealth.com , select "First Quarter Webcast" from
       the home page.

Vanguard Health Systems, Inc. will release its 2008 first quarter operating results on Monday, November 12, 2007, after 4:00 p.m. Eastern time. The Company's earnings press release will be posted under the "Latest News" link on the Investor Relations page of the Company's web site www.vanguardhealth.com

Vanguard Health Systems, Inc. owns and operates 15 acute care hospitals and complementary facilities and services in Chicago, Illinois; Phoenix, Arizona; San Antonio, Texas and Massachusetts.

If you are unable to participate during the live Webcast, the call will be archived on our web site www.vanguardhealth.com . To access the replay, click on the First Quarter Webcast on our home page or on the "Latest News" link on the Investor Relations page of our web site.

CONTACT: Aaron Broad Investor Relations (615) 665-6131 abroad@vanguardhealth.com