Vanguard Health Systems, Inc. Invites You to Join Its 2008 Third Quarter Earnings Conference Call Webcast

Market Wire, April, 2008

In conjunction with Vanguard Health Systems, Inc.'s 2008 Third Quarter Earnings press release, you are invited to listen to its conference call that will be broadcast live over the Internet on May 13, 2008 at 11:00 a.m. Eastern time with senior management of Vanguard discussing the operating results.

WHAT:   Vanguard Health Systems, Inc.'s 2008 Third Quarter Earnings
        Conference Call on the Web

WHEN:   Tuesday, May 13, 2008 at 11:00 a.m. Eastern time

WHERE:   http://www.vanguardhealth.com  or
         http://www.visualwebcaster.com/event.asp?id=47800 

HOW:    Live over the Internet -- Simply log on to the web at one of the
        addresses above.  If you connect through  www.vanguardhealth.com ,
        select the "Latest News" link on the Investor Relations page.

Vanguard Health Systems, Inc. will release its 2008 third quarter operating results on Monday, May 12, 2008, after 4:00 p.m. Eastern time. The Company's earnings press release will be posted under the "Latest News" link on the Investor Relations page of the Company's web site www.vanguardhealth.com .

Vanguard Health Systems, Inc. owns and operates 15 acute care hospitals and complementary facilities and services in Chicago, Illinois; Phoenix, Arizona; San Antonio, Texas and Massachusetts.

If you are unable to participate during the live Webcast, the call will be archived on our web site www.vanguardhealth.com . To access the replay, click on the "Latest News" link on the Investor Relations page of our web site.

Contact: Vanguard Health Systems, Inc. Aaron Broad Director Investor Relations (615) 665-6131