Advancing Practice, Instruction, and Innovation Through Informatics (APIII 2003): Scientific Session and E-Poster Abstracts

Archives of Pathology & Laboratory Medicine, Oct 2004 by Becich, Michael J, Crowley, Rebecca

Design: We apply the Chernoff-Savage approach to derive the asymptotics of an aligned rank statistic in the special case in which a linear analysis of variance model has an orthonormal design and repeated measurements are given. Formally, we cannot apply Adichie's results here, since our centered design matrices are not of full rank. This model is particularly useful in testing for linearity in partly linear models, even when repetitions are not present but there are enough data to do some grouping.

Results: The statistic in this repeated measurement model turns out to be the difference of 2 quadratic forms of a vector with Wilcoxon-type components, with an asymptotic χ^sup 2^ distribution, regardless of the choice of the aligner. Simulation results about the rate of rejecting the null hypothesis in testing for linearity in nonparametric regression with standard Cauchy random errors are discussed.

Conclusions: Investigation into why the asymptotics of the test statistic do not depend on the aligner shows this to be due to cancellation in the location case and also choice of score function in the scale case. Our approach can be easily extended to the multivariate case (multivariate analysis of variance) using a projection method.

Medmicroscopy Telepathology Implementation Between a Regional Care Teaching Facility and a Community Hospital in New Jersey: Initial Hiccups and Recovery

Maneesha Pandey, MD' (manupandey@hotmail.com); Cyril D'Cruz, MO2; M. Pessin-Minsley, MD2; Robert Borrello, BS.2 Departments of 1 Pathology and 2Laboratory Medicine and Pathology, Newark Beth Israel Medical Center, Livingston, NJ (affiliate of Saint Barnabas Medical Center).

Context: Ten pathologists are affiliated with and rotate between a regional care teaching hospital, Newark Beth Israel Medical Center (669 beds), and their satellite community hospital, Clara Maass Medical Center (465 beds). There is only 1 pathologist present at the satellite hospital (Clara Maass Medical Center), with a half-hour drive from the medical center. The medmicroscopy system and software for this setup were installed with the objective of functioning as a telepathology instrument for intraoperative consultations, case discussions, and also continuing medical education between and within the 2 hospitals. The equipment was operational within 2 weeks of installation. Initial technical and software problems, as well as user friendli?ness of the system for the pathologists, was assessed to evaluate the degree of success of the system for this setup.

Technology: The installed medmicroscopy system by Trestle Corporation (Irvine, Calif) consists of 2 microscope sites, one for each hospital, and multiple viewer sites for the users. The medmicroscopy 2.9v software was installed in computers at both microscope and viewer sites. The microscope sites have an automated microscope (Olympus BX51 [Melville, NY] with ×2, ×4, ×lO, ×20, ×40, and ×60 lens objectives) with robotic arm, digital camera, and a control panel attached to a standard personal computer. The viewer sites have only a standard personal computer. The system transmits 24-bit, true-color, high-fidelity images in real time via Internet/intranet protocol and local area network simultaneously to multiple viewer sites.