Business Services Industry
Mochida, Wyeth Enter License Agreement for Novel Pain Treatment
JCNN News Summaries - Japan Corporate News Network, Jan 11, 2008 by Jun Ota
Tokyo, Jan 11, 2008 - (JCN) - Mochida Pharmaceutical announced that it has licensed a portfolio of transient receptor potential vanilloid sub type 1 (TRPV1) receptor antagonists - a potential novel treatment for pain - to Wyeth Pharmaceuticals.
Under the terms of the Agreement, Wyeth has obtained an exclusive worldwide license to develop, manufacture, use and sell pharmaceutical products containing Mochida's TRPV1 antagonists. Mochida will receive an upfront payment and potential development milestone payments, as well as royalties on sales by Wyeth.
Mochida retains an option to co-develop and co-market in Japan with Wyeth.
TRPV1 is a receptor and ion channel which is stimulated by various stimuli including capsaicin (pungent ingredient contained in chili pepper). It is expressed in sensory neurons and pain pathways.
It is hoped that TRPV1 antagonists will be effective in various pain conditions caused by inflammation or neuropathy with less side- effects than existing pain killers, which sometimes cause gastrointestinal disorders or renal disorders.
Drug discovery research targeting TRPV1 receptor is highly competitive with several large pharmaceuticals companies engaged in research and development in this field. JCN Newswire. All rights reserved. A division of Japan Corporate News Network K.K.
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